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Fig. 3 | Virology Journal

Fig. 3

From: Host cytoskeleton in respiratory syncytial virus assembly and budding

Fig. 3

Model for RSV use of microfilaments in viral assembly. a The M-containing RNPs of RSV utilise microfilaments (stress fibres) as a means of transport to reach assembly sites; this movement is facilitated by the M protein interaction with microfilaments. At the assembly site, the RNPs associate with bundles of actin filaments and the envelope glycoproteins to complete viral assembly and initiate budding. b The growth of the viral filament is supported by microfilaments and actin-modulatory proteins; mature virions are released through as yet unknown mechanism of membrane scission

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