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Table 1 Positive selection pressure sites in the HA1 domain of the HA gene in different clusters of Egyptian H5N1 viruses

From: Phylodynamics of avian influenza clade 2.2.1 H5N1 viruses in Egypt

HA site

Mean ω (dN/dS)

Normalized ω (dN/dS)

Classic clade

Variant clade

2.2.1

2.2.1.2

2.2.1.1

2.2.1.1a

120

4.97

4.54

0

216

0

4

129

45.14

41.22

0

221

0

1

140

3.31

3.02

3

0

30

33

141

5.15

4.70

6

9

30

36

154

4.42

4.04

6

154

9

37

155

4.36

3.98

1

128

0

1

162

7.21

6.59

25

171

25

35

185

2.73

2.49

0

9

0

34

188

3.07

2.81

2

3

0

7

  1. The estimates were made using the Single Likelihood Ancestor Counting (SLAC) method. dN/dS ratio of synonymous/ non synonymous per site. The number of viruses changed in each site. P value of < 0.05