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Table 1 Positive selection pressure sites in the HA1 domain of the HA gene in different clusters of Egyptian H5N1 viruses

From: Phylodynamics of avian influenza clade 2.2.1 H5N1 viruses in Egypt

HA site Mean ω (dN/dS) Normalized ω (dN/dS) Classic clade Variant clade
2.2.1 2.2.1.2 2.2.1.1 2.2.1.1a
120 4.97 4.54 0 216 0 4
129 45.14 41.22 0 221 0 1
140 3.31 3.02 3 0 30 33
141 5.15 4.70 6 9 30 36
154 4.42 4.04 6 154 9 37
155 4.36 3.98 1 128 0 1
162 7.21 6.59 25 171 25 35
185 2.73 2.49 0 9 0 34
188 3.07 2.81 2 3 0 7
  1. The estimates were made using the Single Likelihood Ancestor Counting (SLAC) method. dN/dS ratio of synonymous/ non synonymous per site. The number of viruses changed in each site. P value of < 0.05