Fig. 4
DRV (TH11) infection induces the expression of TLR3, IFN-α, NFκB, Mx, OASL, ISG12 and IFITM1 in the spleens of Peking ducklings. a Gene responses in spleens infected with DRV (TH11) at 106 ELD50/0.2 mL. The mRNA levels are presented as the mean ± SD. Asterisks indicate significant differences in the virus-infected group compared with the uninfected group (*P < 0.05, ** P < 0.01 and *** P < 0.001, one-way ANOVA analysis). b Correlation between gene expression and viral replication in the spleen. Statistical analyses were performed using Spearman’s rank correlation coefficient test. Correlation coefficients (rs) and P values are indicated in each graph. The samples were collected from infected ducklings at 0, 24, 48 and 72 h, respectively