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Fig. 3 | Virology Journal

Fig. 3

From: The enhanced expression of death receptor 5 (DR5) mediated by HBV X protein through NF-kappaB pathway is associated with cell apoptosis induced by (TNF-α related apoptosis inducing ligand) TRAIL in hepatoma cells

Fig. 3

The roles of JNK and NF-κB pathways on expressions of DR4 and DR5 proteins in Huh-7-HBX cells. a The activation of JNK pathways induced by HBX. b The activation of NF-κB pathways induced by HBX. c The role of JNK pathways on expression of DR4 and DR5 proteins induced by HBX. Huh-7-HBX and control cells were cultured in 0.01 % dimethyl sulfoxide (DMSO) in the absence or presence of 20 μM SP600125 for 24 h. Then the expressions of DR4 and DR5 proteins were detected by western blotting analysis. d The role of NF-κB pathways on expressions of DR4 and DR5 proteins induced by HBX. Huh-7-HBX and control cells were cultured in 0.01 % dimethyl sulfoxide (DMSO) in the absence or presence of 10 μM BAY11-7082 for 24 h, and then the expressions of DR4 and DR5 proteins were detected by western blotting analysis

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Virology Journal

ISSN: 1743-422X