Fig. 3
From: Central memory CD4+ T cells are preferential targets of double infection by HIV-1
Unstimulated CD4+ T cells were infected with a constant input of 40 ng of X4-pseudotyped EGFP virus and increasing concentrations of X4-pseudotyped mCherry virus over a range from 0 to 512 ng. The slope of the total EGFP+ cells (EGFP+/mCherry- and EGFP+/mCherry+) was not significantly different than 0 (p > 0.5 for both healthy controls). The slope of total mCherry + cells and doubly infected (EGFP + mCherry+) cells were both significantly different than 0 (total mCherry + cells: p < 0.0001 for both controls; doubly infected cells: p = 0.0004 and p = 0.015, respectively). Representative data from 2 (of 4) experiments