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Table 4 Polymorphic sites in the HCV 1b NS3 protease region found in this study

From: Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C

aPosition

bSubtype 1b

aPosition

bSubtype 1b

7

S7/A (6)

114

V114/I (11)

14

L14/V (1)

122

S122/T (1)

30

D30/E (10)

128

S128/Y (1)

48

V48/I (6)

131

P131/T (1)

51

V51/A (1)

132

I132/V/L (5)

56

Y56/F (4)

142

P142/L (1)

61

S61/P/T (5)

150

V150/A (9)

83

V83 /I (1)

170

I170/V (5)

86

P86/Q (11)

178

T178/V (2)

87

A87/S (2)

  

94

M94/L (10)

  

107

V107/I (1)

  
  1. aThe residues are reported as in the wild-type HCV-1a sequence
  2. bThe number of patients with mutant HCV strains is indicated in brackets