Fig. 3
Complete blood counts in mice exposed to EEEV strain FL93-939 either by the aerosol or subcutaneous routes. Numbers shown are the mean ± standard deviation of total white blood cells (a), lymphocytes (b), neutrophils (c), monocytes (d), platelets (e), and red blood cells (f), at each time point (n = 10 per time point per route). Normal ranges (black boxes) were determined from control animals (n = 20) combined from both routes of exposure (white blood cells = 2.4-6.3 x 103/μL, neutrophils = 0.5-1.8 x 103/μL, lymphocytes = 1.2-4.6 x 103/μL, monocytes = 0.1-0.3 x 103/μL, red blood cells = 7.6-8.7 x 106/μL, and platelets = 458.9-914.6 x 103/μL). Note that the aerosol study was terminated at 4 dpi because 90 % of the animals in the 5dpi group were showing moderate to severe signs of clinical disease