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Fig. 9 | Virology Journal

Fig. 9

From: Construction of a recombinant duck enteritis virus (DEV) expressing hemagglutinin of H5N1 avian influenza virus based on an infectious clone of DEV vaccine strain and evaluation of its efficacy in ducks and chickens

Fig. 9

HI antibody titers against AIV H5N1 in chickens vaccinated with DEV-H5(UL55). A total of 50 3-week-old commercial chickens were randomly divided into five groups of A-AI(3C), B-AI(3C), C-AI(3C), D-AI(3C), and E-AI(3C). In groups A-AI(3C), B-AI(3C), and C-AI(3C), chickens were vaccinated intramuscularly with DEV-H5(UL55) at a dose of 1 × 107 TCID50 (Line: 107), 1 × 106 TCID50 (Line: 106), and 1 × 105 TCID50 (Line: 105), respectively. Chickens in group D-AI(3C) were inoculated subcutaneously with a dose of 0.3 ml of inactivated AIV H5N1 Re-6 vaccine (QYH) according to the manufacturer’s instructions (Line: Re-6). Chickens in the control group E-AI(3C) were inoculated with 0.2 ml of PBS (Line: Control). Serum samples of all chickens were collected before inoculation and at 1, 2, 3, 4, 5, and 6 weeks after vaccination to measure the HI titers, which are shown here

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Virology Journal

ISSN: 1743-422X