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Fig. 4 | Virology Journal

Fig. 4

From: Expression of chicken interleukin-2 by a highly virulent strain of Newcastle disease virus leads to decreased systemic viral load but does not significantly affect mortality in chickens

Fig. 4

Macroscopic pictures illustrating lesions in rZJ1-IL2 and rZJ1-GFP-infected chickens. Panel a: eyelid; 4-week-old White Leghorn chicken infected with rZJ1-IL2, day 4 pi. Severe conjunctivitis characterized by hemorrhages, edema and congestion of the upper and lower eyelid. Panel b: comb; 4-week-old White Leghorn chickens infected with rZJ1-IL2, day 6 pi. Severe comb hemorrhages, edema, and cyanosis. Panel c and d: duodenal loop; 4-week-old White Leghorn chicken infected with rZJ1-GFP (c) and rZJ1-IL2 (d), day 4 pi. Note absence of intestinal hemorrhages in ZJ1-IL2-infected birds, compared to ZJ1-GFP-infected birds

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