Table 1 Activity of ca603 and pleconaril against representative viruses from HRV-A and B; and EV-A,-B and-C

HRV-A

HRV02

>313

0.2 ± 0.1*

HRV09

8.9 ± 4.2*

0.2 ± 0.1*

HRV29

1.7 ± 0.04*

0.1 ± 0.1*

HRV63

>157

0.1 ± 0.1*

HRV85

3.7 ± 2.0*

0.1 ± 0.1*

HRV89

0.9 ± 0.8*

0.7 ± 0.3*

HRV-B

HRV14

0.10 ± 0.03*

0.3 ± 0.2*

HRV42

8.2 ± 4.7

>26

HRV70

15 ± 8*

4 ± 3.6

HRV86

0.01 ± 0.003*

0.1 ± 0.1*

EV-A

EV71

74 ± 5

>52

EV-B

CVB3

>313

>131

EV-B

ECHO11

2.5 ± 1.6

1.7 ± 0.4

EV-C

PV1

25 ± 7

>131