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Table 2 Time-dependent changes of serum TBIL, ALT, albumin and PTA

From: Initial combination anti-viral therapy with lamivudine and adefovir dipivoxil decreases short-term fatality rate of hepatitis-B-virus-related acute-on-chronic liver failure

Serum marker Time NA group Non-NA group t value P value
TBIL (μmol/L) Week 1 310.98 ± 134.94 360.39 ± 122.11 1.95 0.054
  Week 2 272.74 ± 166.83 427.22 ± 189.74 4.52 <0.001
  Week 3 239.22 ± 172.03 379.72 ± 200.63 3.59 0.001
  Week 4 240.55 ± 210.19 299.47 ± 195.52 1.10 0.28
ALT (U/L) Week 1 224.43 ± 234.97 267.75 ± 242.43 -0.93 0.36
  Week 2 120.20 ± 116.55 122.05 ± 89.96 -0.09 0.93
  Week 3 87.31 ± 74.70 73.96 ± 38.98 1.02 0.31
  Week 4 63.62 ± 49.75 57.48 ± 28.60 0.56 0.58
Albumin (g/L) Week 1 35.31 ± 5.09 32.05 ± 3.74 3.67 <0.001
  Week 2 36.78 ± 5.02 33.37 ± 3.78 3.92 <0.001
  Week 3 37.51 ± 5.41 32.39 ± 2.90 5.77 <0.001
  Week 4 37.38 ± 5.21 32.42 ± 4.41 3.88 <0.001
PTA (%) Week 1 52.77 ± 27.31 45.59 ± 24.93 1.34 0.18
  Week 2 57.85 ± 29.73 44.31 ± 23.20 2.52 0.013
  Week 3 65.58 ± 30.56 49.70 ± 27.53 2.38 0.020
  Week 4 58.23 ± 31.56 48.50 ± 24.78 1.14 0.260