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Table 2 Time-dependent changes of serum TBIL, ALT, albumin and PTA

From: Initial combination anti-viral therapy with lamivudine and adefovir dipivoxil decreases short-term fatality rate of hepatitis-B-virus-related acute-on-chronic liver failure

Serum marker

Time

NA group

Non-NA group

t value

P value

TBIL (μmol/L)

Week 1

310.98 ± 134.94

360.39 ± 122.11

1.95

0.054

 

Week 2

272.74 ± 166.83

427.22 ± 189.74

4.52

<0.001

 

Week 3

239.22 ± 172.03

379.72 ± 200.63

3.59

0.001

 

Week 4

240.55 ± 210.19

299.47 ± 195.52

1.10

0.28

ALT (U/L)

Week 1

224.43 ± 234.97

267.75 ± 242.43

-0.93

0.36

 

Week 2

120.20 ± 116.55

122.05 ± 89.96

-0.09

0.93

 

Week 3

87.31 ± 74.70

73.96 ± 38.98

1.02

0.31

 

Week 4

63.62 ± 49.75

57.48 ± 28.60

0.56

0.58

Albumin (g/L)

Week 1

35.31 ± 5.09

32.05 ± 3.74

3.67

<0.001

 

Week 2

36.78 ± 5.02

33.37 ± 3.78

3.92

<0.001

 

Week 3

37.51 ± 5.41

32.39 ± 2.90

5.77

<0.001

 

Week 4

37.38 ± 5.21

32.42 ± 4.41

3.88

<0.001

PTA (%)

Week 1

52.77 ± 27.31

45.59 ± 24.93

1.34

0.18

 

Week 2

57.85 ± 29.73

44.31 ± 23.20

2.52

0.013

 

Week 3

65.58 ± 30.56

49.70 ± 27.53

2.38

0.020

 

Week 4

58.23 ± 31.56

48.50 ± 24.78

1.14

0.260