Inoculum
|
Case/Sex
|
HCV genotype
|
Plasma HCV RNAa (vge/mL)
|
HCV RNA load in cells
|
---|
1 d.p.i.
|
7 d.p.i.
|
10 d.p.i.
|
---|
Positive stranda (vge/μg RNA)
|
Negative strandb
|
Positive stranda (vge/μg RNA)
|
Negative strandb
|
Positive stranda (vge/μg RNA)
|
Negative strandb
|
---|
CHC-1
|
C26/F
|
1a/1b
|
1.1 × 106
|
8777
|
neg
|
1290
|
pos
|
1010
|
pos
|
CHC-2
|
C33/M
|
3a
|
2 × 104
|
746
|
neg
|
204
|
neg
|
neg
|
NT
|
CHC-3
|
N28/F
|
2b
|
2.4 × 106
|
<50
|
NT
|
<50
|
NT
|
<50
|
NT
|
-
dpi days post-infection, F female, M male, NT not tested, pos positive, neg negative
-
aQuantified by in house real-time RT-PCR
-
bDetermined by the strand-specific RT-PCR/NAH