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Table 1 Virological characteristics of individuals with CHC providing plasma serving as HCV inocula and HCV RNA loads in T cells infected with these inocula

From: Patient-derived hepatitis C virus inhibits CD4+ but not CD8+ T lymphocyte proliferation in primary T cells

Inoculum Case/Sex HCV genotype Plasma HCV RNAa (vge/mL) HCV RNA load in cells
1 d.p.i. 7 d.p.i. 10 d.p.i.
Positive stranda (vge/μg RNA) Negative strandb Positive stranda (vge/μg RNA) Negative strandb Positive stranda (vge/μg RNA) Negative strandb
CHC-1 C26/F 1a/1b 1.1 × 106 8777 neg 1290 pos 1010 pos
CHC-2 C33/M 3a 2 × 104 746 neg 204 neg neg NT
CHC-3 N28/F 2b 2.4 × 106 <50 NT <50 NT <50 NT
  1. dpi days post-infection, F female, M male, NT not tested, pos positive, neg negative
  2. aQuantified by in house real-time RT-PCR
  3. bDetermined by the strand-specific RT-PCR/NAH