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Fig. 2 | Virology Journal

Fig. 2

From: Associations between hepatitis B virus basal core promoter/pre-core region mutations and the risk of acute-on-chronic liver failure: a meta-analysis

Fig. 2

Summary odds ratio (OR) of acute-on-chronic liver failure for A1762T, G1764A, A1762T/G1764A and G1896A mutations. Squares represent study-specific estimates (size of the square reflects the study-specific statistical weight); horizontal lines represent 95 % confidence intervals (CIs); diamonds represent summary estimates with corresponding 95 % CIs. Test for heterogeneity: (G1896A) p = 0.002, I2 = 48.1 %; (A1762T/G1764A) p < 0.001, I2 = 80.7 %; (A1762T) p = 0.164, I2 = 25.7 %; (G1764A) p = 0.004, I2 = 56.4 %. A random-effects model was used for G1896A, A1762T/G1764A and G1764A, and a fixed-effects model was used for A1762T. All statistical tests were two-sided

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