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Table 1 Results of the dilution test compared to gold standard (N = 495)

From: Dilution testing using rapid diagnostic tests in a HIV diagnostic algorithm: a novel alternative for confirmation testing in resource limited settings

Dilution

Result

Number

Number with gold standard result

Concordance

Kappa value*

Positive (%)

Negative (%)

1/10

Positive

259

247 (95.3)

12 (4.6)

97.6

0.952

Negative

236

0

236 (100)

  

1/40

Positive

249

247 (99.2)

2 (0.8)

99.6

0.992

Negative

246

0

246 (100)

  

1/160

Positive

246

246 (100)

0

99.8

0.996

Negative

249

1 (0.4)

248 (99.6)

  

1/640

Positive

244

244 (100)

0

99.4

0.988

Negative

251

3 (1.2)

248 (98.8)

  

1/2560

Positive

240

240 (100)

0

98.6

0.972

Negative

255

7 (2.8)

248 (97.2)

  

1/10,240

Positive

221

221 (100)

0

94.8

0.895

Negative

274

26 (9.5)

248 (90.5)

  

TOTAL

495

247 (49.9)

248 (50.1)

  
  1. *All p values for the kappa statistics are <0.001