Figure 1From: Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner Effect of HCV infection on the insulin signaling pathway. Equal amounts of cellular lysates from uninfected and HCV-infected Huh7.5.1 cells at a M.O.I of 2 for 48 h were subjected to western blot analysis using anti-pIRS-1Ser307, IRS-1, pAkt, Akt, and core-specific antibodies. Anti-GAPDH antibody was used as an internal control to verify protein loading.Back to article page