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Figure 6 | Virology Journal

Figure 6

From: IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis

Figure 6

Neutralization of IL-22 decreased the percentage of the Th22 cells, IL-22 and IL-22R. A. Th22 cells in anti-IL-22 Ab, IgG and PBS treated mouse groups were investigated by flow cytometry at week 2 and 12. B. The levels of circulating IL-22 measured by ELISA. C. Morphometric quantitation of cardiac IL-22R protein expression detected by IHC. D. Representative IL-22R immunohistochemistry images in heart tissue in anti-IL-22 Ab, IgG control and PBS treated mouse groups (Dark brown granules, original magnification × 400).

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Virology Journal

ISSN: 1743-422X