Figure 1

Relative expression level of NLRP3, TNF-α and IL-1β in the lung and brain of control, rV _K627E and V _K627 groups at different time points.^*, P < 0.05; ^**, P < 0.01. Data are represented as mean ± standard deviation (SD). All samples were tested in triplicate. A, B and C: Expression level of NLRP3, IL-1β and TNF-α in the lung of control, rV_K627E and V_K627 groups at different time points, respectively; D, E and F: Expression level of NLRP3, IL-1β and TNF-α in the brain of control, rV_K627E and V_K627 groups at different time points, respectively.