Figure 1

Sequence alignment of nucleoproteins from swine and human influenza A virus strains. The swine and human NPs are 89.1% identical (yellow highlighting) and 94.8% similar (yellow and green highlighting). Nonconservative amino acids differences are represented in white. Amino acids with * represent signature amino acids associated with avian influenza A NP, and # and † represent signature amino acids associated with avian influenza A NP based on Chen et al. [16] and Pan et al. [17]. † Denotes the only deviation of A/Sw/NC 44173/00 from the consensus swine residues based on Pan et al. [17].