Table 1 Differential expression of genes in MEK/ERK signaling pathway in EV71-infected iDCs at different time points
From: MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
Gene symbol | EV71/control (Fold changes) | |||
|---|---|---|---|---|
1/2Â h | 2Â h | 8Â h | 24Â h | |
KRAS | −1.09 | +1.94 | +2.21 | +1.18 |
NRAS | −1.05 | +1.08 | +1.42 | −1.07 |
Raf-1 | +1.07 | +6.51 | −1.25 | −1.21 |
MEK1 | +1.26 | +1.26 | −1.02 | −1.09 |
MEK2 | +1.15 | +1.19 | −1.04 | −1.15 |
ERK1 | +1.27 | −1.16 | −1.10 | −1.20 |
ERK2 | +1.73 | +1.23 | −1.36 | −1.65 |
c-Fos | +5.46 | +7.65 | +4.62 | +3.71 |
c-Jun | +1.64 | +2.05 | +2.78 | +3.67 |
c-myc | +1.20 | −1.31 | +2.54 | −1.15 |
Elk1 | −2.57 | +1.94 | +1.69 | +2.47 |
SOS1 | +1.89 | +16.70 | −1.78 | −1.15 |
IL-1α | −1.00 | +5.49 | +3.82 | −1.17 |
IL-2 | +1.23 | +3.12 | +2.76 | +1.79 |
IL-6 | +1.68 | +2.33 | +2.84 | +1.67 |
IL-12 | +1.34 | +1.76 | +2.36 | +1.84 |
IFN-α1 | −1.56 | +1.58 | +1.37 | −1.75 |
IFN-β | −1.26 | +2.72 | +2.04 | −1.49 |
IFN-γ | −1.10 | +2.69 | +1.40 | −1.82 |
TNF-α | +1.28 | +2.27 | +2.62 | +1.41 |