Skip to main content

Table 1 Demographics and clinical characteristics of the 6 analyzed clusters

From: Multiplex PCR analysis of clusters of unexplained viral respiratory tract infection in Cambodia

Year 2009 2010 2011 2012
province (site code) Kandal (KD02) Kampong Speu (KS02) Kandal (KD02) Ratanakiri (RK01) SteungTreng (ST02) Kratie (KT02)
enrollment period, (day duration) 24-31 Aug (8 d) 12-16 Oct (7 d) 05-18 Mar (14 d) 25 Jul-12 Sep (50 d) 13-16 Feb (4 d) 4 Apr (1 d)
season Rainy Rainy Dry Rainy Dry Dry
number of cases 20 22 11 11 11 10
median age [range] 36.5 [4–71] 11 [2–60] 26 [6–45] 4 [2–5] 19 [18–49] 23 [2–43]
female/male, n (%) 9 (45)/11 (55) 12 (55)/10 (45) 8 (73)/3 (27) 4 (36)/7 (64) 4 (36)/7 (64) 8 (80)/2 (20)
fever present, median (duration day) 4 [2–4] 4 [2–6] 3 [2–4] 4 [2–6] 3 [2–3] 3 [2–5]
virus type detected (n) EV-D68 (6); HRV-C (4); HRV-A; RSV-B RSV-B (5); EV-D68; HRV-A; HRV-B; HRV-C ADV; HRV-B RSV-A (9); CV-B4; EV-D68; HCoV-OC43; HRV-C HRV-B (3); HCoV-OC43 HRV-A (3); HRV-C; HCoV-229E
Symptoms       
headache, n (%) 18 (90) 21 (95.5) 11 (100) 7 (63.5), 4 NA 11 (100) 10 (100)
cough, n (%) 18 (90) 22 (100) 11 (100) 11 (100) 8 (73) 5 (50)
malaise, n (%) 15 (75) 21 (95.5) 4 (36.5) 11 (100) 0 0
chills, n (%) 0 21 (95.5) 5 (45.5) 3 (27.5) 7 (63.5) 2 (20)
muscle ache n (%) 3 (15) 0 1 (9) 0, 4 NA 0 7 (70)
joint pain, n (%) 8 (40) 0 1 (9) 0, 6 NA 2 (18) 1 (10)
seizure, n (%) 0 0 0 1 (9) 0 0
sore throat, n (%) 12 (60) 4 (18) 11 (100) 3 (27.5), 8 NA 1 (9) 6 (60)
shortness of breath, n (%) 0 0 0 10 (91) 0 0
nausea, n (%) 0 0 0 9 (82) 0 0
vomiting, n (%) 1 (5) 0 10 (91) 8 (73) 0 0
abdominal cramps, n (%) 1 (5) 0 2 (18) 1 (9), 4 NA 0 0
Site Diagnosis*       
pharyngitis, n (%) 11 (55) 3 (13.5) 10 (91) 0 0 0
influenza, n (%) 7 (35) 5 (23) 1 (9) 0 0 7 (70)
pneumonia, n (%) 1 (5) 0 0 11 (100) 0 0
bronchitis, n (%) 0 1 (4.5) 0 0 0 0
upper respiratory infection, n (%) 0 13 (59) 0 0 0 0
malaria, n (%) 0 0 0 0 11 (100) 3 (30)
other, n (%) 1 typhoid fever 0 0 0 0 0
  1. NA = Not available; HRV-A/B/C = human rhinovirus type A/ B/C; EV-D68 = enterovirus D68; HCoV = human coronavirus; ADV = adenovirus; RSV-A/B = respiratory syncytial virus A/B; CV-B4 = coxsackievirus B4.
  2. *all samples tested negative for influenza virus, dengue virus and Plasmodium spp.in laboratory assays.