Figure 3

Viability and proliferation of mock and DENV-infected Huh7 cells following hnRNP C1/C2 knockdown. Huh7 cells were transfected with either hnRNP C1/C2-specific siRNA or irrelevant negative control siRNA followed by mock or DENV infection at MOI 0.03. Cells were collected at 0, 12, 24, 36 and 48 h post-infection and subjected to propidium iodide (PI) staining and trypan blue exclusion dye assay. Results are shown as follows: (A) the percentage viability of mock-infected cells; (B) the percentage viability of DENV-infected cells; (C) the total number of viable mock-infected cells; and (D) the total number of viable DENV-infected cells. Data represent mean and SEM of three independent experiments.