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Figure 2 | Virology Journal

Figure 2

From: Simultaneous alteration of residues 279 and 284 of the VP2 major capsid protein of a very virulent Infectious Bursal Disease Virus (vvIBDV) strain did not lead to attenuation in chickens

Figure 2

Amino acid sequence alignment of the polyprotein sequences of the Tunisian vvIBDV wild-type PO7 strain (PO7wt), the cell culture-adapted and attenuated P2 and OKYMT IBDV strains, and the cell culture-adapted, but virulent, D279N/A284T mutated P2/PO7 chimeric IBDV virus (P2/PO7mt). Amino acid residues (positions 253, 279, and 284) known to be involved in cell culture adaptation and virulence are highlighted in green. The residue 256 which could have contributed to OKYMT attenuation is highlighted in orange.

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Virology Journal

ISSN: 1743-422X