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Figure 3 | Virology Journal

Figure 3

From: Osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection associated with delayed type I interferon responses

Figure 3

Underlying OA condition further perturbs RANKL/OPG ratio after RRV infection in primary hOBs. Primary hOBs were infected with EGFP-RRV at MOI 1 and cells were harvested at different time points for RNA extraction. Transcriptional profiles of (A) RANKL and (B) OPG were determined using qRT-PCR. (C) RANKL/OPG ratio is shown. Data are normalized to HPRT and shown as fold expression relative to healthy mock-infected group. Data (n =4) are presented as mean ± SEM. *P <0.05, one-way ANOVA, Tukey's post-test.

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