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Table 1 IL-28B genetic distribution and allele frequency in stratification based on the combination of HTLV-1 and HCV infection

From: Paradoxical expression of IL-28B mRNA in peripheral blood in human T-cell leukemia virus Type-1 mono-infection and co-infection with hepatitis C Virus

 

Genotype r(rs8099917)

Allele fequency

 

No

TT

TG

GG

T

G

 

All cases

340

263(77.4%)

71(20.9%)

6(1.8%)

0.86

0.14

 

1) non-Infection

59

45(76.3)

10(16.9)

4(6.8)

0.84

0.15

 

2) HTLV-1 mono

73

55(75.3)

17(23.3)

1(1.9)

0.87

0.13

P = 0.90

   ATL patients carriers

47

37(78.7)

10(21.3)

0(0.0)

0.89

0.11

P = 0.11

 

26

18(69.2)

7(26.9)

1(3.8)

0.82

0.18

P = 0.46

3) HCV-mmono

179

141(78.7)

37(20.7)

1(1.0)

0.89

0.11

P = 0.68

4) co-infection

29

22(75.9)

7(24.1)

0(0.0)

0.88

0.14

P = 0.9

  1. There was no significant difference in the genetic distribution and allele frequency among respective infectious states
  2. P values were compared with non infection