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Figure 4 | Virology Journal

Figure 4

From: Design of different strategies of multivalent DNA-based vaccination against rabies and canine distemper in mice and dogs

Figure 4

Kinetics of CDV-neutralizing antibody titers in dogs inoculated pCMV3ISS-CDVH or Tetradog®. Groups of 4 dogs were administered either 100 μg of pCMV3ISS-CDVH, intradermally, or 1 ml of Tetradog®, intramuscularly and compared to a group of 3 sham-vaccinated animals (100 μg of pCMV3ISS). All the dogs were blood-sampled at days 0, 30, 60, 90 and 365 post-vaccination. Titers were expressed as the highest dilution of sera that inhibited the cytopathic effect of CDV-Onderstepoort strain. Results correspond to the mean antibody titers (the highest dilution of sera that inhibited the cytopathic effect of CDV-Onderstepoort strain) of the corresponding dogs in each group.

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Virology Journal

ISSN: 1743-422X