Figure 5
From: Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model
Drug susceptibility test of antiviral drugs on HBV replication using the HBV replication mouse model. A: HBV DNA replication intermediates were detected by southern blotting in the mouse model treated with NS (control), lamivudine (LAM), adefovir (ADV), entecavir (ETV) and telbivudine (LdT), respectively. B: The relative levels of HBV DNA replication intermediates in the mouse model among different groups. The levels of HBV DNA replication intermediates in NS treated wild-type group and mutant mice were set to 1 respectively, and the relative levels of treated groups were calculated accordingly.