Figure 1
From: Isolation and molecular characterization of type I and type II feline coronavirus in Malaysia
CrFK-4 cell cultures showing cytopathic changes following infection with reference and local FCoV isolate UPM 11C/08. Morphology of cells infected with local FCoV UPM 11C/08 isolate at passage 3 (A). where the initial CPE was observed at passage 2. At fifth viral passages, complete CPE occurred within 48-72hours PI. Morphology of cells infected with reference FIPV-79-1146 strain (B). Infected cells show CPE characterized by cells rounding, clumped and detachment (arrows). Note that the changes in cells infected with UPM11C/08 are comparable to reference strain. Control uninfected cells remained normal (C). Unstained.