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Table 1 Preoperative demographic and clinical characteristics of the patients in treatment and control groups

From: Effect of antiviral therapy on the survival and incidence of major complications in HBV-associated cirrhotic patients after splenectomy for hypersplenism and portal hypertension

 

Treatment group (n = 28)

Control group (n = 29)

P

Sex (M:F)

24:4

20:9

0.132

Age [Mean ± SD (range) (years)]

39.75 ± 9.01 (19–54)

42.65 ± 8.56 (23–64)

0.716

Child-Pugh Grade (%)

  

0.519

 A

8 (28.57)

11 (37.93)

 

 B

13(46.43)

14 (48.28)

 

 C

7 (25.00)

4 (13.79)

 

HBeAg (%)

  

0.082

 Positive

14 (50.00)

8 (27.59)

 

 Negative

14 (50.00)

21 (72.41)

 

HBV DNA (IU/ml) (%)

  

0.073

 <103

4 (14.29)

13 (44.83)

 

 ≥103 -105

10 (35.71)

8 (27.59)

 

 ≥105 - 107

12 (42.86)

6 (20.69)

 

 ≥107

2 (7.14)

2 (6.89)

 

White blood cell count (×109/L)

2.70 ± 1.85

3.30 ± 4.06

0.854

Platelet count (×109/L)

38.11 ± 14.53

45.80 ± 26.22

0.648

INR

1.12 ± 0.49

1.23 ± 0.21

0.533

ALT( IU/L)

49.00 ± 22.89

50.20 ± 87.24

0.148

AST( IU/L)

47.23 ± 22.60

50.42 ± 77.47

0.079

Serum bilirubin (μmol/L)

28.58 ± 15.76

21.20 ± 7.19

0.139

Albumin (g/L)

32.63 ± 9.16

35.84 ± 6.14

0.129

  1. ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBV, hepatitis B virus; INR, international normalized ratio; IU, international unit; SD, standard deviation.