Localization of HPV origin DNA repeats in the nucleus after cotransfection with GFP-E2–expressing plasmid. Components labeled are indicated in the upper corners of the panels with their respective colors. (A)-(C): MEF cells cotransfected with pHPVori128 and pgfpE2; the oriDNA-GFPE2 complex is shown in green (B) and PML is shown in red (C); the merged picture is in (A). (D-F): The same as in (A-C), but cells are MEF PML−/− cells and show Daxx in red (F). (G-I), the same as in (A-C), but the cells are MEF Daxx−/− cells.