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Figure 3 | Virology Journal

Figure 3

From: Epitope mapping by random peptide phage display reveals essential residues for vaccinia extracellular enveloped virion spread

Figure 3

MAb-1G10 binding to chemically synthesized peptides containing Cluster I and Cluster II consensus sequences. (A) Peptides RF2-1 and RF2-5 demonstrate increased binding to MAb-1G10 when compared to an unrelated control antibody. (B) Treatment of reduced peptide RF2-1 with N-ethylmaleimide (NEM) significantly reduces MAb-1G10 binding compared to treatment with PBS alone (control), indicating the requirement for a conformational structure constrained by a disulphide bond. Binding levels were compared using Student’s t-test.

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