Figure 2From: Secretory pathway antagonism by calicivirus homologues of Norwalk virus nonstructural protein p22 is restricted to norovirusesLocalization and effect of norovirus homologues of NV p22 on the Golgi apparatus. 293T cells were transfected to express the indicated proteins and immuno-stained for the cis Golgi or ER marker proteins GM130 and calnexin, respectively (Alexa-Fluor 594 secondary antibody, red fluorescence). Nuclei were counterstained with DAPI (blue fluorescence) and cells were imaged by deconvolution microscopy. The * in C indicates a mitotic cell, and “U201 p22LΔ” has the MERES motif mutated to encode YXΦAAAA in place of the MERES motif.Back to article page