Immunohistochemistry for detecting the MCPyV LT antigen on cervical SCC and AC tissue sections. Hematoxylin and eosin staining (A) showed histological findings of the specimens containing SCC cells (cases SCC3 and SCC35) and AC cells (case AC15). Immunohistochemistry with the CM2B4 monoclonal antibody (B) and with the polyclonal antibody (D) showed immunoreactivity in the tumor cells. Insets show higher magnification views of the tumor cells. The isotype-matched negative control antibody (mouse IgG2b) for CM2B4 showed no immunoreactivity (C).