Table 3 Statistical results for comparison between therapy outcome and genotype in ProtFun analysis
From: New insights regarding HCV-NS5A structure/function and indication of genotypic differences
| Region | Feature | Comparison | Chi-square | p-value | Stat power |
|---|---|---|---|---|---|
| NS5A | Functional category | Outcome | 18.832 | 0.004 | 0.711 |
| R and NR | 10.697 | 0.013 | 0.617 | ||
| R and ETR | 15.279 | 0.002 | 0.627 | ||
| NR and ETR | 5.103 | 0.164 | 0.676 | ||
| Genotype | 218.730 | 0.000 | 1 | ||
| Domain I | GO* | Outcome | 1.370 | 0.504 | 0.694 |
| Genotype | 51.316 | 0.000 | 0.999 | ||
| Domain II | Functional category | Outcome | 27.769 | 0.000 | 0.861 |
| R and NR | 15.903 | 0.000 | 0.881 | ||
| R and ETR | 16.776 | 0.000 | 0.581 | ||
| NR and ETR | 0.241 | 0.623 | 0.663 | ||
| Genotype | 21.755 | 0.000 | 0.780 | ||
| Non/enzyme | Genotype | 22.711 | 0.000 | 0.801 | |
| GO | Outcome | 1.792 | 0.408 | 0.665 | |
| Genotype | 116.636 | 0.000 | 1 | ||
| Domain III | GO* | Outcome | 24.680 | 0.000 | 0.572 |
| R and NR | 5.488 | 0.064 | 0.587 | ||
| R and ETR | 11.307 | 0.010 | 0.616 | ||
| ETR and NR | 12.374 | 0.006 | 0.609 | ||
| Genotype | 54.217 | 0.000 | 0.998 |