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Table 3 Survival rate of three month-old C3H mice immunized with NS1 or PBS

From: Protective immunity to Japanese encephalitis virus associated with anti-NS1 antibodies in a mouse model

Immunogen Anti-NS1 IgG antibody titer rangea No. of Survival mice/No. of Immunized mice (Survival rate) P b
NS1 0-12800 12/18 (66.7%) 0.41
NS1 0-2400 3/9 (33.3%) 1
NS1 2400-12800 9/9 (100%) 0.008
PBS 0 4/9 (44.4%)  
  1. a Two weeks before challenge, mouse sera were collected for anti-NS1 IgG antibody titration. The NS1-immunized group of mice (18 mice in total) was divided into two groups according to anti-NS1 IgG titers: one group with anti-NS1 IgG <2400 (9 mice) and one group with anti-NS1 IgG >2400 (9 mice).
  2. bP value was obtained by log rank test when comparing the survival curve of each group with PBS group.