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Table 1 Genetic, demographic and Clinical background of 2009 pdm H1N1 influenza strains

From: Heterogeneous virulence of pandemic 2009 influenza H1N1 virus in mice

  A/Nanchang/8002/2009
(NC2)
A/Nanchang/8008/2009
(NC8)
A/Nanchang/8011/2009
(NC11)
Day of sample collection 9 Dec 2009 19 Dec 2009 22 Dec 2009
Age (yrs) 27 15 33
Gender M F F
Temperature (oC) 39.4 38.5 NA
Hospitalization
Complications    NA
Antiviral Treatment   
Lethality in mice Severe Mild Severe
Viral loads in mice lungs High Low High
Replication in A549 cells High Moderate High
£TCID50/ml 1 x 104.83 1 x 104.33 ND
EID50/ml 1 x 106.4 1 x 107.75 1 x 106.4
PB2 Genbank ID JF800142 CY089613 CY089621
V227I    
  V295L   
  R299K    
  I310R   
  K353R   
  N556K   
  T588I   
  K660R   
PB1 Genbank ID JF800143 CY089614 CY089622
T257A   
PA Genbank ID CY089607 CY089615 CY089623
A70V  
P224S
  E243G    
  E319V   
  D547E   
  1. £Observed in MDCK cells, NA: not available, ND: not detected, Mutations are compared with prototypic strain: A/California/07/2009 H1N1.