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Table 5 Molecular signatures derived on amino acid residue variations in chikungunya whole E2 proteins are shown below

From: Genetic characterization of Chikungunya virus from New Delhi reveal emergence of a new molecular signature in Indian isolates

Collection Year

Sample

E2 protein: Amino Acid Residue Position

2

118

149

157

205

211

255

264

299

317

318

344

375

384

386

1966/2005

Africa

T

S

K

V

G

T

I

V

N

V

T

T

S

T

V

1953

ECSA

T

S

K

V

G

I

I

V

S

V

V

A

S

M

V

1985/2007

Asia

I

G

R

A

D

T

V

V

N

I

R

T

S

V

V

2010

Delhi♦

T

S

K

V

G

T

I

A

N

V

V

T

T

M

A

1963

West Bengal

I

G

R

A

D

T

I

V

N

V

R

T

S

V

V

2003/2006

Maharashtra

I/T

G/S

K

V

D/G

T

I

V

N

V

R/V

T

S/T

V/M

V/A

2006

Gujarat

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

2006/2007/2009

Kerala

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

2006

Rajasthan

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

2006

Tamil Nadu

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

2006

Karnataka

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

2006/2008/2009

Andhra Pradesh

T

S

K

V

G

T

I

V

N

V

V

T

T

M

A

  1. Amino acid residue positions of the complete E2 proteins, the Country/State and year of collection of CHIKV are denoted. (−) denotes sequence information not available.
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Virology Journal

ISSN: 1743-422X