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Table 5 Molecular signatures derived on amino acid residue variations in chikungunya whole E2 proteins are shown below

From: Genetic characterization of Chikungunya virus from New Delhi reveal emergence of a new molecular signature in Indian isolates

Collection Year Sample E2 protein: Amino Acid Residue Position
2 118 149 157 205 211 255 264 299 317 318 344 375 384 386
1966/2005 Africa T S K V G T I V N V T T S T V
1953 ECSA T S K V G I I V S V V A S M V
1985/2007 Asia I G R A D T V V N I R T S V V
2010 Delhi T S K V G T I A N V V T T M A
1963 West Bengal I G R A D T I V N V R T S V V
2003/2006 Maharashtra I/T G/S K V D/G T I V N V R/V T S/T V/M V/A
2006 Gujarat T S K V G T I V N V V T T M A
2006/2007/2009 Kerala T S K V G T I V N V V T T M A
2006 Rajasthan T S K V G T I V N V V T T M A
2006 Tamil Nadu T S K V G T I V N V V T T M A
2006 Karnataka T S K V G T I V N V V T T M A
2006/2008/2009 Andhra Pradesh T S K V G T I V N V V T T M A
  1. Amino acid residue positions of the complete E2 proteins, the Country/State and year of collection of CHIKV are denoted. (−) denotes sequence information not available.