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Table 2 Amino acid substitutions of VN1194-W and other viruses

From: Virulence of H5N1 virus in mice attenuates after in vitro serial passages

Virus

PB2

PB1

PA

NP

 

26

60

63

189

143

256

325

677

709

30

46

86

94

102

106

262

271

366

VN1194*

D

H

I

K

L

E

I

T

V

I

F

M

I

K

L

S

A

A

VN1194-W

D

D

I

K

L

E

I

T

V

I

F

I

I

K

L

S

A

A

1194-SP

D

D

I

K

L

E

I

T

V

I

F

I

I

K

L

S

A

A

1194-LP

N ※

D

T

R

S

K

I

M

I

T

S

I

I

R

P

P

T

D

1194-ML

N

D

T

R

L

E

I

M

I

T

S

I

I

K

L

S

A

A

1194-MB

D

D

I

K

L

E

T

T

V

I

F

I

V

K

L

S

A

A

  1. *: Reference A/Vietnam/1194/2004 (H5N1) sequences downloaded from NCBI (PB2: AAT73549; PB1: AAT73495; PA: AAT74486; NP: AAT70629)
  2. ※: Mutations, compared to reference sequences, were highlighted byFrame line and bold type.
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