Figure 6
From: Reduced inflammation and altered innate response in neonates during paramyxoviral infection
ICAM-1 mRNA and protein levels were lower in neonatal lungs. a) Adult and neonatal C57BL/6 mice were infected as described in Figure 1. Whole lung RNA from adults (white bars), neonates (black bars), and naïve age-matched neonatal controls (striped bars) was analyzed by qPCR for ICAM-1 mRNA levels. Data are means ± SD. *p < 0.039. ICAM-1 immunostaining. Sections of naïve day 0 untreated adult (b) and untreated neonatal lungs (c) were stained with an anti-ICAM-1 antibody. Primary anti-ICAM-1 antibody was detected using an alkaline phosphatase red substrate and the sections were counterstained with hematoxylin (magnification 200X)