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Table 3 Efficacy of antiviral drugs against Korean ECV 18

From: Molecular characterization and antiviral activity test of common drugs against echovirus 18 isolated in Korea

Compounds

IC50a

CC50b

TIc

Azidothymidine

NDd

>100

-

Acyclovir

NDd

>100

-

Amantadine

4.97 ± 0.77

>100

20.12

Lamivudine

NDd

>100

-

Ribavirin

7.63 ± 0.87

>100

13.11

  1. These results represent mean ± S.D (n = 3).
  2. a Concentration of compound in μg/mL producing 50% inhibition of virus-induced cytopathic effects.
  3. b The 50% cytotoxic concentration for target cells in μg/mL.
  4. C Therapeutic index (TI) = CC50/IC50
  5. d Not Determined
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Virology Journal

ISSN: 1743-422X