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Table 3 Efficacy of antiviral drugs against Korean ECV 18

From: Molecular characterization and antiviral activity test of common drugs against echovirus 18 isolated in Korea

Compounds IC50a CC50b TIc
Azidothymidine NDd >100 -
Acyclovir NDd >100 -
Amantadine 4.97 ± 0.77 >100 20.12
Lamivudine NDd >100 -
Ribavirin 7.63 ± 0.87 >100 13.11
  1. These results represent mean ± S.D (n = 3).
  2. a Concentration of compound in μg/mL producing 50% inhibition of virus-induced cytopathic effects.
  3. b The 50% cytotoxic concentration for target cells in μg/mL.
  4. C Therapeutic index (TI) = CC50/IC50
  5. d Not Determined