Avipoxviruses: infection biology and their use as vaccine vectors

Table 2 Avipoxvirus vector-based vaccines licensed for commercial veterinary use

Recombinant viral vector	Inserts	Targeted Pathogen	Species	Distributor	Country	References
ALVAC	G	Rabies virus	Cats	Merial, Inc.	USA, Canada	[109]
ALVAC	HA and F	Canine distemper virus	Dogs, ferrets	Merial, Inc.	USA, Argentina, Brazil, Colombia, Canada, Uruguay	[132]
ALVAC	PrM-E	West-Nile virus	Horses	Merial, Inc.	USA, Canada	[133, 134]
ALVAC	Env, Gag/pol	Feline leukaemia virus	Cats	Merial, Inc.	Europe, USA, Canada	[135–137]
FWPV	H5 HA	Avian influenza virus	Chickens	Merial, Inc.	USA, Canada	[110]
ALVAC (plus tetanus toxoid and Carbopol adjuvant)	HA	Equine influenza virus	Horses	Merial, Inc.	Europe, USA	[111]
FWPV	HN and F	Newcastle disease virus	Chickens	Biomune	USA	[13, 138]
FWPV- Laryngotracheitis Vaccine	LT+AE	Infectious Laryngotracheitis virus	Chickens	Biomune Co. (Lenexa, KS, USA)	USA	[139]
FWPV- Mycoplasma gallisepticum Vaccine	MG+AE	Avian Encephalomyelitis and Mycoplasma gallisepticum	Chickens	Biomune Co.	USA	[140]

Note: HA from influenza virus H5; HA, hemagglutinin; HN, haemagglutinin-neuraminidase protein; ALVAC, attenuated canarypox virus; FWPV, fowlpox virus; F, fusion protein; G, glycoprotein G; Env, envelope glycoprotein; Gag, group specific antigen; Pro, protease; prM-E, pre-membrane and envelope proteins; MG+AE, Mycoplasma gallisepticum + Avian Encephalomyelitis; LT+AE, Laryngotracheitis virus+Avian Encephalomyelitis.

ISSN: 1743-422X