Table 3 Phenotypes of CD4+ regulatory cells in early HCV infection
From: Characterization of antigenic variants of hepatitis C virus in immune evasion
Median (range) (%) | |||
|---|---|---|---|
CD4+ cells | HCV- (n = 3) | HCV+ (n = 6) | p value* |
CD25+ | 9.50 (9.1 - 10) | 20.9 (17 - 34) | 0.02 |
TGFβ+ | 2.89 (1.3 - 8.4) | 30.0 (25 - 37) | 0.02 |
IL-10+ | 3.02 (1.6 - 5.1) | 5.64 (2.0 - 16) | 0.04 |
IFNγ+ | 5.04 (1.6 - 9.8) | 5.14 (2.9 - 8.7) | 0.81 |
TGFβ+ IL-10+ | 1.33 (0.3 - 3.4) | 5.03 (1.4 - 9.3) | 0.05 |
TGFβ+ IFNγ+ | 1.52 (0.7 - 5.0) | 2.01 (0.9 - 6.8) | 0.54 |
CD25- | 56.0 (52 - 58) | 51.3 (48 - 54) | 0.07 |
TGFβ+ | 1.43 (0.7 - 4.2) | 26.5 (20 - 33) | 0.02 |
IL-10+ | 0.42 (NA**) | 0.92 (0.5 - 6.8) | NA |
IFNγ+ | 2.15 (0.9 - 3.2) | 2.31 (0.4 - 7.3) | 0.81 |
TGFβ+ IL-10+ | 0.08 (NA) | 0.40 (0.2 - 2.5) | NA |
TGFβ+ IFNγ+ | 0.07 (0.05 - 1.1) | 0.70 (0.03 - 1.1) | 0.2 |