Figure 4

STAT3 mRNA and p -STAT3 protein expression in the myocardium of VMC mice. A. Strong expression of STAT3 occurred from 1st week to 6th week after CVB3 infection. M: Maker; 1: week 0; 2: week 1; 3: week 2; 4: week 3; 5: week 4; 6: week 6. B. Densitometric quantitation of STAT3. STAT3 mRNA expression was elevated in VMC mice from 1st week to 6th week, ^ΔP < 0.01, versus control group. ^ΔP < 0.05, versus week 0, 1 and 2. C. Representative of p-STAT3 immunohistochemistry images in heart tissue of VMC mice (Dark brown stain in cytoplasm, original magnification × 400). D. Morphometric quantitation of p-STAT3 protein expression in heart. ^ΔP < 0.05, versus control group, ^ΔP < 0.05, versus week 0, 1, 2 VMC mice.