| |
SR(%)
|
NR(%)
|
OR
|
p
|
|---|
|
Allele
|
n = 24 × 2 = 48
|
n = 28 × 2 = 56
| | |
|
-819C
|
4(8.3)
|
16(28.6)
|
0.23
|
0.01
|
|
-819T
|
44(91.6)
|
40(71.4)
|
4.4
|
0.01
|
|
-592C
|
8(16.6)
|
32(57.1)
|
0.15
|
<0.01
|
|
-592A
|
40(83.3)
|
24(42.9)
|
6.67
|
<0.01
|
|
-1082A
|
47(97.9)
|
53(94.6)
|
2.66
|
0.62
|
|
-1082G
|
1(2.1)
|
3(5.4)
|
0.38
|
0.62
|
|
Genotype
|
n = 24
|
n = 28
| | |
|
-592A/A
|
19(79.1)
|
4(14.3)
|
22.8
|
<0.01
|
|
-592A/C
|
2(8.3)
|
18(64.3)
|
0.05
|
<0.01
|
|
-592C/C
|
3(12.5)
|
6(21.4)
|
0.52
|
0.48
|
|
-819T/T
|
21(87.5)
|
15(53.6)
|
6.07
|
0.02
|
|
-819T/C
|
2(8.3)
|
10(35.7)
|
0.16
|
0.02
|
|
-819C/C
|
1(4.2)
|
3(10.7)
|
0.36
|
0.62
|
|
-1082A/A
|
23(95.8)
|
25(89.3)
|
2.78
|
0.62
|
|
-1082A/G
|
1(4.2)
|
3(10.7)
|
0.36
|
0.62
|
|
-1082G/G
|
0(0)
|
0(0)
|
-
|
-
|
|
Heplotype
|
n = 24
|
n = 28
| | |
|
ATA
|
19(79.1)
|
13(46.4)
|
4.38
|
0.02
|
|
GCC
|
0(0)
|
3(10.7)
|
-
|
-
|
|
ACC
|
5(20.8)
|
12(42.8)
|
0.35
|
0.14
|
- NOTE: n is the number of patients or controllers. P values were caculated by Fisher Probability. P values less than 0.05 were considered statistically significant. SR: sustained response; NR: non-responders.
