| |
patients (%)
|
control (%)
|
OR
|
P
|
|---|
|
Allele
|
n = 52 × 2
|
n = 48 × 2
| | |
|
- 1082G
|
4(3.9)
|
3(3.1)
|
1.24
|
0.99
|
|
- 1082A
|
100(98)
|
93(96.8)
|
0.81
|
0.99
|
|
- 819C
|
18(17.3)
|
18(18.7)
|
0.91
|
0.85
|
|
- 819T
|
86(92.7)
|
78(81.3)
|
1.97
|
0.85
|
| |
38(36.5)
|
22(22.9)
|
1.88
|
0.05
|
|
- 592A
|
66(63.4)
|
74(77.1)
|
0.52
|
0.05
|
|
Genotype
|
n = 52
|
n = 48
| | |
|
- 592 A/A
|
23 (44.2)
|
30 (62.5)
|
0.48
|
0.08
|
|
A/C
|
20(38.4)
|
14(29.2)
|
1.52
|
0.40
|
|
C/C
|
9(17.3)
|
4(8.3)
|
2.3
|
0.24
|
|
- 819T/T
|
36(69.2)
|
33(68.8)
|
1.02
|
0.99
|
|
T/C
|
12(23.1)
|
12(23.1)
|
0.9
|
0.99
|
|
C/C
|
4(7.7)
|
4(7.7)
|
1.25
|
0.99
|
|
- 1082 A/A
|
48(92.3)
|
45(93.8)
|
0.8
|
0.99
|
|
A/G
|
4(7.7)
|
3(6.3)
|
1.25
|
0.99
|
|
G/G
|
0(0)
|
0(0)
| | |
|
Heplotype(-1082/-819/-592)
| | | |
| |
n = 52
|
n = 48
| | |
|
GCC
|
4 (7.6)
|
3(6.2)
|
1.25
|
0.99
|
|
ACC
|
13 (25)
|
14(29.1)
|
0.81
|
0.66
|
|
ATA
|
41 (78.8)
|
43(89.5)
|
0.43
|
0.18
|
|
GTA
|
2 (3.8)
|
2(4.1)
|
0.92
|
0.99
|
- NOTE: n is the number of patients or controllers. P values were caculated by Fisher Probability. P values less than 0.05 were considered statistically significant. SR: sustained response; NR: non-responders.
