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Table 3 Advantages and disadvantages of different novel vaccines

From: Research in advance for FMD Novel Vaccines

Novel vaccines

security of production

security of vaccinated animal

shelf life

duration of immune response

vaccination effectiveness

Differentiation of infected animals from vaccinated ones

Subunit vaccine

Yes

Yes

Normal

Normal

Low

Yes

Live vector vaccine

Yes

Yes

Normal

Long

High

Yes

Nucleic acid vaccine

Yes

Risk to recombinant to other genomes

Long

Long

Low

Yes

Novel attenuated vaccine

Yes

Risk to toxicity reversion but low

Normal

Long

High

Yes

Synthetic peptide vaccine

Yes

Yes

Normal

Short

Low

Yes