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Figure 6 | Virology Journal

Figure 6

From: Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus

Figure 6

The accumulation of mutated NS1 in cytoplasmic bodies. Mutated NS1 protein accumulated in cytoplasmic bodies that did not co-localise with markers for cis -golgi (anti-GM130), ER (anti-PDI), or endosomes (anti-EEA-1), and did co-localise with a marker for lysosomes (anti-LAMP1). Vero cells infected with NS1F-ELCmut were fixed 24 h p.i. and dual labelled with markers for the indicated organelles (green) and anti-NS1/2 polyclonal antiserum (red). Overlay images were generated using Photoshop.

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Virology Journal

ISSN: 1743-422X