Table 3 Percent and number of NP-specific CD8+ T cells in pooled MLN, lung and BAL samples after challenge of immunized mice with A/PR/8/34
Previous exposure to viral antigens | |||||
|---|---|---|---|---|---|
none | Live virus IN | live virus IM | UV-inact virus IM | heat-inact virus IM | |
Percent NP 147-155 -specific CD8+ T cells | |||||
MLN | 0.2 | 4.2 | 3.0 | 1.7 | 0.3 |
Lung | 9.6 | 52.0 | 47.9 | 26.9 | 22.0 |
BAL | 15.5 | 60.2 | 63.5 | 32.5 | 25.6 |
Number of NP 147-155 -specific CD8+ T cells per mouse | |||||
MLN | 431 | 10,028 | 6,296 | 5,608 | 1,451 |
Lung | 60,597 | 231,304 | 183,918 | 113,603 | 62,890 |
BAL | 14,940 | 23,427 | 44,129 | 25,473 | 13,612 |