Figure 4From: Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virusProtection of mice against heterosubtypic challenge. Percent weight loss (A) and lung virus titers (B) were measured in A/WI/05 (H3N2)-immunized mice, 7 days after infection with A/PR/8/34 (H1N1). Groups of mice were vaccinated IM with live and heat-treated whole virus. Control groups included mice without prior vaccination and a group of mice infected IN with live A/WI/05.Back to article page