Graphic representation of the potential Ser, Thr, and Tyr residues for phosphorylation and O-glycosylation modification for human claudin-1. A) Predicted potential sites for phosphate modification on Ser and Thr residues. The light gray horizontal line indicates the threshold for modification potential. The blue, green and red vertical lines showed the potential phosphorylated Ser, Thr and Tyr residues, respectively. B) Predicted potential sites for O-glycosylation modification of Ser and Thr. O-β-GlcNAc modification potential of Ser/Thr residues is shown by green vertical line, while the light blue wavy line indicates the threshold for modification potential. C) The Yin Yang sites that were positively predicted are shown with red asterisk at the top, while the NP-Yin Yang site are shown with purple asterisk on the top of vertical lines. The green vertical lines show the O-β-GlcNAc potential of Ser/Thr residue and the light blue horizontal wavy line indicates the threshold for modification potential.