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Table 3 Comparison of important characteristics between 166 patients with positive HBeAg and negative HBeAg

From: A336C/A336T/T337C variations in HBV core gene and spontaneous hepatitis B e antigen loss in chronic hepatitis B patients

 

HBeAg positive

(n = 77)

HBeAg negative

(n = 89)

χ2

P value

A336C/A336T/T337C variations

  

12.1

0.001

A336/T337

68

58

  

C336/T336/C337

9

31

  

G1896 variation

  

42.3

<0.001

G1896

63

28

  

A1896

14

61

  

HBV genotype

  

14.8

<0.001

B

28

59

  

C

49

30

  

serum HBV DNA levels

  

23.9

<0.001

<6

31

69

  

≥6

46

20

  

Age

  

4.6

0.03

<35

44

36

  

≥35

33

53

  

Sex

  

0.001

0.94

Male

59

68

  

Female

18

21

  

Serum ALT levels

  

3.2

0.07

≤50 U/L

52

48

  

>50 U/L

25

41